http://www.nytimes.com/2006/04/09/world/americas/09lymph.html Lymphatic filariasis—a disease which results grossly swollen limbs—affects 120 million people; there is no cure, and to eradicate it, “every infected person must be given a dose of worm-killing medicine once per year for six years.” (Or, you can have everyone eat treated salt.) 23:23